Adrenaline is used:
Contraindications:
Except in life threatening illness, it is dangerous if injected intravenously - always check that the needle is not in a vein before injecting.
Adrenaline has alpha, beta-1 and beta-2 activity, and in terms of inotropism tends to work in the patients where the other therapies fail. Its action here is the result of beta-1 receptor down regulation - which means that the percentage of regulation of inotropy by beta-2 receptors is increased.
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