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Results

Authoring team

  • there were 939 atherosclerotic events in the clopidogrel group during 17,636 patient-years at risk, an average rate per year of 5.32%

  • there were 1031 events in the aspirin group during 17,519 patient-years risk, an average rate per year of 5.83%

  • the relative risk reduction was 8.7% (95% CI 0.3-16.5) in favour of clopidogrel (p=0.043)

  • there was no significant differences between aspirin and clopidogrel in relation to the risk of death from any cause

  • calculating the number to needed to treat from the CAPRIE trial data, it would be necessary to use clopidogrel instead of aspirin in approximately 200 patients for 1 year to avert one additional major clinical event

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