This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Complications

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

In addition to the features mentioned under clinical features and associations, there are a number of conditions which can develop in later life, including:

  • recurrent upper respiratory tract infection
  • hypothyroidism (2)
    • patients with Down's syndrome have a higher prevalence ofautoimmune thyroid disease compared with the general population,with thyroid autoantibodies being found in 13-34% of patients with Down's syndrome
    • patients may develop hypothyroidism inchildhood or adulthood. Check TSH annually in adult patients with Down's syndrom
  • acute lymphoblastic leukaemia
  • the risk of solid tumours is reduced

Reference:

  • 1) Hasle, H, Clemmensen, IH, Mikkelsen, M. (2000). Risks of leukaemia and solid tumours in individuals with Down's syndrome. Lancet, 355, 165-9.
  • 2) Siskind SM et al. Investigating hypothyroidism. BMJ2021;373:n993http://dx.doi.org/10.1136/bmj.n993

Related pages

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.