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Fat metabolism

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These include:

  • permissive effect on lipolytic hormones e.g. adrenaline by increasing the synthesis of a cAMP-dependent protein kinase
  • conversion of inactive lipase to active form at specific peripheral sites

Eventually, there is a redistribution of adipose deposits to give cushingoid characteristics:

  • truncal obesity
  • 'buffalo hump'
  • 'moon face'

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