Lipid lowering effects of fibrates and nicotinic acid (1):
Fibrate | Nicotinic Acid | |
Total cholesterol | 11% reduction | 10% reduction |
Triglycerides | 36% reduction | 20% reduction |
Low-density lipoprotein cholesterol | 8% reduction | 14% reduction |
High-density lipoprotein cholesterol | 10% increase | 16% increase |
Apart from flushes in the niacin group, both fibrates and niacin were shown to be well-tolerated and safe (1).
Reference:
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