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Risk profiles of the LQT genotypes

Authoring team

In a study of subjects aged 0-40 years with hereditary long QT syndrome:

  • LQT1 or LQT2 have a high risk of serious cardiac events:
    • LQT1 have a 63% risk
    • LQT2 have a 46% risk
    • LQT3 have an 18% risk

  • among subjects experiencing a cardiac event the mortality for LQT3 patients was highest

Reference:

  • Zareba, W. et al. (1998). Influence of the genotype on the clinical course of the long-QT syndrome. New Engl. J. Med. 339, 960-5.

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