This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Diagnosis

Authoring team

  • Hamm's test or acid-haemolysis test

  • sucrose haemolysis test or sugar water test:
    • a medium of low ionic strength, e.g. isotonic sucrose is used to aggregate serum globulins onto the surface of red cells
    • this activates complement which then lyses PNH red cells
    • the sucrose haemolysis test is more sensitive but less specific than the Ham test and best used as a screen

  • immunophenotype analysis for deficient antigen expression:
    • CD59 for red cells and platelets
    • CD67 for granulocytes
    • CD14 for monocytes
    • CD24 for B cells

Related pages

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.