Histology, immunohistochemistry and electron microscopy have given us insights into the microanatomy of keloid scars. Compared to normal, non-fibroproliferative scarring, keloid scars show:
There is a large degree of overlap of histological features between keloid and hypertrophic scars. Indeed, some authorities have suggested that the dynamic nature of change within the two clinical types of fibroproliferative scarring makes pathological distinction between them impossible; they may simply represent different time points on a continuum of abnormality.
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