This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Factors associated with higher risk of reccurrence or metastasis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

High-risk squamous cell carcinoma are those that are high risk have a high recurrence rate after treatment and may metastasise. Various features are associated with a high-risk squamous cell carcinoma of the skin:

Histological features

  • poorly differentiated, perineural invasion, depth greater than 4 mm or extending to subcutaneous tissue (Clark level 5)

Sites

  • lip, ears, non-sun-exposed sites, e.g. penis, scrotum and soles of feet; in areas of previous injury, e.g. burns, irradiation and chronic ulcers

Other factors

  • greater than 2 cm diameter, immunosuppression, previously treated lesion

Reference:

  1. NICE (February 2006).CSG Improving Outcomes for People with Skin Tumours including Melanoma: The Manual

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.