pentoxifylline is believed to increase microcirculatory blood flow although the exact mechanism of action is unknown
medications with potential interactions with pentoxfylline include non-steroidal antiinflammatorys (NSAIDS). Details of interactions and contraindications can be found in the British National Formulary
use of pentoxifylline in the treatment of venous leg ulcers is an unlicensed indication
use of pentoxifylline (400 mg three times daily for up to six months) to improve healing should be considered in patients with venous leg ulcer (1)
Reference:
1) SIGN (August 2010). Management of chronic venous leg ulcer.
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