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Predisposing genes

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Genetic loci associated with keloid scarring

The following genes have been associated with keloid scarring:

  • TGF-beta 1 and 2 isoforms
  • TGF-beta 3 (1)
  • HLA-B14
  • HLA-B21
  • HLA-Bw16
  • HLA-Bw35
  • HLA-DRB1 (2)
  • HLA-DR5
  • HLA-DQw3
  • blood group A

Ref:

(1) Bayat A, Walter JM, Bock O et al. Br J Plast Surg (2005); 58(7): 914-921.

(2) Brown JJ, Ollier WE, Arscott G, Bayat A. Clin Exp Dermatol (2010); 35(3): 305-310.

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