Most long term studies comprise patients attending hospital clinics so that results are biased to more severe disease. Permanent remission occurs in 10% of patients. Acute guttate psoriasis is often self limiting but in 70% of cases, it proceeds to chronic plaque disease.
Generalised pustular and erythrodermic psoriasis have a poor prognosis.
Reference
Svedbom A et al. Long-term Outcomes and Prognosis in New-Onset Psoriasis. JAMA Dermatol. 2021 Apr 14;157(6):1-8.
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