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Bromocriptine is used where there is problems with L-dopa therapy e.g. gradual ineffectiveness and the on/off phenomena.
This drug should be used with caution in patients over 70 years of age. Important side effects include hypotension, nausea and psychotic reactions.
Apomorphine, a drug only prescribed in specialist centres, appears to an effective treatment measure when patients develop on/off phenomenon.
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