This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Gastrin

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Gastrin is a gastrointestinal hormone secreted by G cells in the gastric antrum. It acts on the fundus of the stomach to stimulate:

  • mucosal growth
  • gastric acid secretion:
    • negative feedback regulation ensures that acidic gastric contents inhibit further gastrin production
    • note that acetylcholine, histamine, gastrin and calcium all stimulate parietal cell acid secretion
    • increased vagal activity stimulates acid production

Stimulants of gastrin secretion include:

  • peptides and amino acids in the stomach lumen
  • gastric distension results in vagal stimulation and some gastrin secretion
  • massive small bowel resection is sometimes associated with hypergastrinaemia

Related pages

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.