occurs in up to 30% of hypertensive patients treated with thiazide diuretics
the presence of hyperuricaemia per se does not require withdrawal of the thiazide or treatment
if gout develops however then it is prudent to stop thiazide treatment and initiate alternative therapy for hypertension
if a patient has a history of gout then treatment with thiazides are best not used - if necessary concurrent treatment with allopurinol can allow continued treatment with a thiazide
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