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Mikulicz syndrome

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Mikulicz disease comprises the triad of:

  • symmetrical enlargement of all salivary glands
  • narrowing of the palpebral fissures due to enlargement of the lacrimal glands
  • parchment-like dryness of the mouth

It is due to an autoimmune process and is looked upon as a clinical variant of Sjogren's syndrome.

Mikulicz syndrome has the same clinical picture. However, the salivary and lacrimal glands are enlarged due to known causes such as sarcoidosis and tuberculosis.

These terms are confused and overused. It is better to define the specific lesion rather than use the eponym.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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