Risk of adenocarcinoma of the oesophagus:
Oesophageal adenocarcinoma (AC) risk is more than 11 times higher in people with Barrett's oesophagus (BO) versus the general population, a cohort study showed.[1]
Oesophageal AC develops in around 1 per 1,000 BO patients per year [1,2]
However, previous studies estimate a much higher risk of around 1 oesophageal AC case per 160-190 BO patients per year.[4,5]
Oesophageal AC risk among BO patients increases with BO extent (higher in long-segment than short-segment) and severity (progressively higher through non-dysplastic[4,6] low-grade dysplastic or high-grade dysplastic).
Oesophageal AC risk among BO patients may be higher in males than females, and in smokers than non-smokers.[7]
Factors affecting risk of oesophageal AC if BO:
Reference
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