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Risk factors for development of infantile GORD

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Children with the following conditions are with an increased risk of GORD:

neurologic impairment and delay (1)
history of premature birth (2)
oesophageal atresia with repair
hiatus hernia
bronchopulmonary dysplasia (preterm infants with lung disease)
asthma
cystic fibrosis (1)
oesophageal sphincter disorders
raised intra-abdominal pressure (3)

NICE state that when deciding whether to investigate or treat, take into account that the following are associated with an increased prevalence of GORD (4):

premature birth
parental history of heartburn or acid regurgitation
obesity
hiatus hernia
history of congenital diaphragmatic hernia (repaired)
history of congenital oesophageal atresia (repaired)
a neurodisability

Reference:

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