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Blood components

Authoring team

The blood components which are most commonly given to patients with DIC are:

  • platelets

  • fresh frozen plasma:
    • a good source of fibrinogen, clotting factors and anticoagulants such as antithrombin and protein C

  • cryoprecipitate:
    • a source of fibrinogen used only if fresh frozen plasma is insufficient to maintain fibrinogen levels above 0.5 g/l

The following are widely accepted indications for administering blood components:

  • active bleeding
  • invasive procedures

Regimes include:

  • when the platelet count is below 50x10^9/l give 1 unit of platelets per 10 kg
  • fresh frozen plasma is given in doses of 15 ml/kg

The effect of treatment on the clotting function should be assessed immediately and after several hours to assess the severity of the consumptive coagulopathy.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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