antibacterials, such as metronidazole and ciprofloxacin, may be prescribed in the treatment of fistulating Crohn's Disease to treat accompanying abscesses or in perianal Crohn's Disease or sepsis (1)
antibiotics, including metronidazole, are indicated in
the treatment of symptoms attributable bacterial overgrowth
septic complications
perineal disease (3)
significant side-effects of metronidazole include peripheral neuropathy if used long term (over three months), a bad taste in the mouth and a disulfiram-like interaction with alcohol
antibiotics such as ciprofloxacin have also been used in the place of steroids to treat moderate relapses of ulcerative colitis
NICE suggest (4):
to maintain remission in people with ileocolonic Crohn's disease who have had complete macroscopic resection within the last 3 months, consider azathioprine in combination with up to 3 months' postoperative metronidazole
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