This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

NBT-PABA protocol

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The NBT-PABA test of pancreatic exocrine function is performed in the following way:

  • the patient is fasted overnight
  • 500 mg NBT-PABA with 5 microCi C14-PABA in 25 g casein is given orally in 500 ml water
  • urine is collected for 6 hours
  • urine collection is analysed for PABA content and C14 radioactivity
  • the fractional excretion of PABA and C14 label is calculated

Interpretation of results:

  • the PABA excretion ratio is calculated by: PABA excreted/PABA ingested
  • the C14 excretion ratio is calculated by: C14 excreted/C14 ingested
  • the ratio of the PABA ratio to the C14 ratio:
    • exceeds 0.76 in normal individuals
    • is less than 0.76 in patients with exocrine pancreatic impairment

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.