This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Proton pump inhibitors (PPI) and increased Clostridium difficile infection

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Increased Clostridium difficile infection if using proton pump inhibitors

  • overall, it appears that proton pump inhibitors (PPI) are associated with increased risk of incident and recurrent Clostridium difficile infection (CDI), based on a consistent direction of association observed in the majority of studies included in the meta-analysis
    • the study authors concluded "... Despite the substantial statistical and clinical heterogeneity, our findings indicate a probable association between PPI use and incident and recurrent CDI. This risk is further increased by concomitant use of antibiotics and PPI, whereas H2 receptor antagonists may be less harmful..."

Reference:


Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.