Adult pyloric stenosis occurs most commonly as a result of peptic ulceration, where at first fibrotic scarring is compensated by dilatation and hypertrophy of the stomach muscle. The process of compensation eventually fails to keep pace - similar to the failure of a hypertrophic ventricle to pump through a stenosed valve. This sort of obstruction is not specific to the pylorus.
Other causes of pyloric stenois include:
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