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Pyrimethamine with dapsone

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Maloprim is used in the prophylaxis of Falciparum malaria.

The usual adult dose is 12.5 mg pyrimethamine with 100 mg dapsone once per week.

Maloprim is contraindicated in the first-trimester of pregnancy. If maloprim is prescribed in the second and third trimesters of pregnancy then folate supplements should be given.

The summary of product characteristics should be consulted before prescribing this drug.


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