chloroquine-resistant falciparum malaria is now widespread (effectively universal) P. falciparum has also developed resistance to a variety of other agents in certain areas
currently no recorded drug resistance to P. ovale and only 1 report of drug-resistant P. malariae (to chloroquine)
chloroquine-resistant P. vivax is found in the Indonesian archipelago; the Malay Peninsula, including Myanmar, and eastward to Southern Vietnam and may have spread further
P. vivax with reduced susceptibility to primaquine is found in South-East Asia and Oceania and higher doses of primaquine are required to achieve radical cure of this parasite from those areas. A higher dose may also be required for P. vivax from India, Pakistan, Afghanistan and South America
Reference:
Public Health England. Guidelines for malaria prevention in travellers from the UK 2019.
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