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Normal or raised TSH, raised free thyroid hormones

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Normal or elevated TSH in the presence of raised free thyroid hormones is a rare disorder but may be clinically important.

The causes of this pattern of abnormality are:

  • artefact - need to repeat the tests
  • interfering antibodies
  • familial dysalbuminaemic hyperthyroxinaemia
  • amiodarone therapy
  • thyroid hormone receptor mutations
  • acute psychiatric disease
  • TSH secreting pituitary tumour
  • intermittent thyroxine overdosage

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