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Anabolic steroids and hepatic effects

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Hepatic:

  • various abnormal liver function tests (elevated alkaline phosphatase, aminotransferases, conjugated bilirubin, and plasma proteins) have been associated with the use of anabolic androgenic steroids (AAS)

  • jaundice occasionally occurs as a result of hypersensitivity-type reaction and is usually seen after 2-5 months of therapy

  • cholestasis has been reported especially with the use of 17alpha-alkylated agents

  • in the majority of cases, the rise in transaminases is transient, with levels normalizing within a few weeks of discontinuation of AAS

  • peliosis hepatis and hepatocellular adenomas have been seen with the use of 17alpha-alkylated AAS

Reference:

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