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Washed cells and filtered blood

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Washed red cells and filtered blood are indicated in patients with recurrent or severe allergic or febrile reactions to red cells, and in severely IgA-deficient patients with anti-IgA antibodies for whom red cells from an IgA-deficient donor are not available

  • produced either manually (24-hour shelf life) or by a closed, automated system in which the red cells are sequentially washed to remove most of the plasma (<0.5 g residual plasma per unit) and then resuspended in 100 mL SAG-M (shelf life 14 days from washing).

Irradiated red cells are useful in patients at risk of transfusion-associated graft-versus-host disease

  • red cells are irradiated by gamma or X-rays within 14 days of donation and it then has a shelf life of 14 days from irradiation.

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