Prognosis of Hodgkin's lymphoma

• 8 in 10 (80%) people diagnosed with Hodgkin lymphoma in England and Wales survive their disease for ten years or more (2010-11)
  
  
• almost 9 in 10 (85%) people diagnosed with Hodgkin lymphoma in England and Wales survive their disease for five years or more (2010-11)
  
  
• around 9 in 10 (91%) people diagnosed with Hodgkin lymphoma in England and Wales survive their disease for one year or more (2010-11)
  
  
• Hodgkin lymphoma survival is higher in women than men. Hodgkin lymphoma survival in England is higher for people diagnosed aged under 40 years old (2009-2013)
  
  
• 95% of people in England diagnosed with Hodgkin lymphoma aged 15-39 survive their disease for five years or more, compared with more than a quarter of people diagnosed aged 80 and over (2009-2013)
  
  
• Hodgkin lymphoma survival is improving and has increased in the last 40 years in the UK. In the 1970s, almost half of people diagnosed with Hodgkin lymphoma survived their disease beyond ten years, now it's 8 in 10
  
  
• Hodgkin lymphoma mortality is strongly related to age, with the highest mortality rates being in older people
  • in the UK in 2014-2016, on average each year more than 4 in 10 (43%) deaths were in people aged 75 and over - this is a lower proportion of deaths in older age groups compared with most cancers
  • age-specific mortality rates rise steadily from around age 10-14 and more steeply from around age 55-59. The highest rates are in the 80 to 84 age group for males and females
  • mortality rates are similar between males and females in most age groups

Open Image in Modal

Prognostic indicators include:

• age - better prognosis in younger patients
• histology - lymphocytic predominant > nodular sclerosis > mixed cellularity > lymphocytic depletion
• stage - lower has better prognosis
• symptoms - generalised symptomatic disease has worst prognosis

Reference:

• CRUK. Hodgkin lymphoma statistics (Accessed 28/5/2019).