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Syphilitic aortic valve regurgitation

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Syphilis should be considered in a patient with aortic regurgitation and a chest radiograph that shows a dilated ascending aorta.

The distinguishing features of syphilitic aortic regurgitation are:

  • a diastolic murmur which is often loudest at the right sternal edge (in contrast to the normal left sternal edge) because of the aortic dilatation
  • an systolic snap due to rapid expansion of the aorta during systole

Aortic regurgitation may be well tolerated for many years. Eventually the volume overload of the left ventricle results in cardiac failure.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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