Salmonella spp (nontyphoidal)
- antibiotic therapy is indicated only in high-risk children to reduce the risk of bacteraemia and extra-intestinal focal infections
- antibiotics recommended to treat adults include a fluoroquinolone (e.g., ciprofloxacin) or azithromycin depending on the local susceptibility patterns and travel history (1)
- preferred therapy – ceftriaxone
- alternative agents - azithromycin, ciprofloxacin (1)
Salmonella typhi
- preferred therapy – third-generation cephalosporins
- alternative agents - chloramphenicol (1)
The typical antibiotic course is for 3 to 7 days or until after fevers resolve (2)
Salmonellosis is a notifiable disease
References:
- Shane AL, Mody RK, Crump JA, et al. 2017 Infectious Diseases Society of America clinical practice guidelines for the diagnosis and management of infectious diarrhea. Clin Infect Dis. 2017 Nov 29;65(12):1963-73.
- Gilbert DN, Chambers HF, Eliopoulos GM, et al. The Sanford guide to antimicrobial therapy, 47th ed. Sperryville, VA: Antimicrobial Therapy, Inc.; 2017.