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Salmonella is the most common bacterial cause of diarrhoea in HIV infected individuals (1).
In these individuals systemic symptoms are more marked, and though 10% have negative stool cultures the organism is often isolated on blood culture.
Following treatment 10-20% suffer a relapse, and for this reason some say treatment with 250mg b.d. ciprofloxacin should be continued for a minimum of three months (1)
Infectious Disease Society of America guidelines for the management of invasive non-typhoidal salmonella disease in HIV-infected adults recommend 2-6 weeks of fluoroquinolone therapy (2)
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