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Management

Authoring team

  • empirical antimicrobial therapy - consider:
    • source of septicaemic organism, i.e. site
    • neutropenia
    • previous antibiotics
    • any underlying disease
    • prevailing patterns of antibiotic resistance
    • whether hospital or community acquired

  • oxygenation

  • fluid replacement

  • drainage of abscesses

  • vasopressors and inotropes

New, currently experimental approaches:

  • monoclonal antibodies to endotoxin

  • monoclonal antibodies ot tissue mediators

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