This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Streptomycin

Authoring team

Streptomycin is an antibiotic derived from Streptomyces griseus.

Indications:

  • tuberculosis, where drug resistance is suspected

Cautions:

  • increase dose interval in renal impairment. If the impairment is severe the dose itself should also be reduced
  • beware drug interactions (see current issue BNF)

Contra-indications:

  • pregnancy
  • myasthenia Gravis - aminoglycosides may impair neuromuscular transmission; indeed large doses given during surgery may be responsible for a transient myasthenic syndrome

Side-effects include:

  • vestibular damage
  • reversible nephrotoxicity

NB. Both vestibular and renal toxicity are dose related and occur most often in the elderly and in those with renal impairment.

  • hypomagnesaemia in prolonged therapy
  • pseudomembranous colitis
  • hypersensitivity reactions
  • paraesthesia of the mouth

Route of administration:

  • i.m. injection

The summary of product characteristics should be consulted before prescribing this drug.

Related pages

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.