Vancomycin

Structure:

• complex glycopeptide - contains an aminodisaccharide and amino acid molecules

Cautions;

• FBC, liver and kidney function test required
• Necrosis and thrombophlebitis due to extravasation at the injection site
• Reduced dose in the elderly

Contra-indications;

• Avoid parenteral administration in patients with renal impairment or a history of deafness

Routes of administration;

• Oral; þ Capsules
• i.v. infusion

The summary of product characteristics should be consulted before prescribing this drug.