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Invasive ductal carcinoma NOS

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Invasive ductal carcinoma NOS can only be diagnosed when the histological features of lobular carcinoma and the special types of ductal carcinoma e.g. medullary, have been excluded. Usually, it is associated with a high grade and poor prognosis.

Macroscopically it may exhibit:

  • usually well-circumscribed
  • rarely greater than 3-4 cm
  • stony hard and gritty consistency - 'scirrhous'
  • areas of calcification

Microscopically there may be:

  • dense fibrous stroma
  • diffusely scattered nests or cords or tumour cells
  • evidence of vascular or neural invasion
  • cells:
    • polygonal
    • compressed
    • uniform small, dark nuclei few mitoses

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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