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Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Features develop between 4 and 10 years after the original infection, and are attributed to progressive, sclerosing demyelination with severe neurological impairment and include:

  • mental deterioration - regression of abilities with dementia
  • strange behaviour
  • convulsions
  • myoclonic jerks, which are generalised, repetative and occur at five to ten second intervals
  • pyramidal signs, with cerebellar ataxia

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