This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Very low density lipoproteins

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Very low density lipoprotein is the lipoprotein form of circulating endogenous lipids. It is made in the liver and has a lower lipid to protein ratio than chylomicrons.

VLDL has a half-life of less than one hour.

It contains approximately 50% triglyceride which is then extracted by the action of lipoprotein lipase by extrahepatic cells. It is synthesised with apolipoprotein B (apo B100) in its membrane and acquires apolipoprotein C during transit. The latter protein permits the functioning of lipoprotein lipase. Protein makes up approximately 9% of its mass. The proportion by mass of VLDL that is cholesterol or cholesterol esters is approximately 20%.

With progressive loss of triglyceride, via lipoprotein lipase, the VLDL particle is converted into intermediate and then low density lipoprotein.


Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.