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Associations

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Cleft hand is associated with a number of clinical anomalies and syndromes including:

  • syndromes:
    • EEC (ectrodactyly-ectodermal dysplasia-clefting) Syndrome
    • Cornelia de Lange association
    • Silver-Russell Syndrome
    • Poland's Syndrome
    • oculodigital complex
    • orodigital complex
    • Wildervank Syndrome
  • general anomalies:
    • cleft lip and palate
    • hearing deficits
    • congenital heart disease eg ventricular septal defects
    • imperforate anus
    • nystagmus
    • cataract
    • deafness
    • ptosis
    • undescended testes
  • limb anomalies:
    • cleft feet
    • club feet
    • syn(poly)dactyly
    • tibial defects
    • hypoplastic patella
    • pseudoarthrosis of the clavicle
    • synostosis of the elbow
    • radioulnar synostosis
    • short humerus
    • short forearm
    • absent ulna
    • short femur

 

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