Indications for prophylactic antibiotics include:
As a general rule prophylactic antibiotics should be given in the perioperative period and then discontinued. It is best if the first dose can be given on induction of anaesthesia. Prolonged administration of antibiotics is accompanied by undesirable side effects, such as the emergence of antibiotic resistant organisms, or the development of pseudomembranous colitis; it is for this reason that a duration of therapy should be stated.
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