there is a strong association between HLA-B27 and ankylosing spondylitis,
become evident that HLA-B27 is common to the entire group of seronegative spondyloarthropathies:
which include Reiter's disease, subgroups of intestinal and psoriatic arthropathies, subgroups of juvenile rheumatoid arthritis
other associations include:
anterior uveitis
amyloidosis in rheumatoid arthritis
there is also an association which aortic valve ring calcification
Reference:
(1) Moll JM, Harlock I, MacRae IF, Wright V. Associations between ankylosing spondylitis, psoriatic arthritis, Reiter's disease, the intestinal arthropathies, and Behçet's syndrome. Medicine (Baltimore) 1974; 53: 343-364.
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