This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Prazosin

Authoring team

This is an alpha-adrenoceptor blocker.

The first dose of prazosin may provoke hypotensive collapse so it should be given in the evening with the patient in bed. Blood pressure should be monitored.

The indications for prazosin are:

  • cardiovascular disease:

  • hypertension:
    • 500 mcg 2-3x/day
    • increase dose to 1 g 2-3x/day after a week
    • maximum daily dose is 20 mg

  • congestive cardiac failure:
    • 500 mcg 2-4x/day
    • increase dose to 1 g 4x/day after a week
    • maximum daily dose is 20 mg

  • Raynaud's syndrome:
    • 500 mcg 2x/day
    • increase dose to 1-2 g 2x/day after a week

  • symptomatic benign prostatic hyperplasia:
    • causes relaxation of smooth muscle in the bladder neck
    • 500 mcg 2x/day
    • after a week increase dose according to response
    • usual maintenance dose is 2 mg 2x/day

Related pages

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.