A study found patients with an ACKR1 variant (rs2814778-CC) had a higher risk of azathioprine discontinuation due to haematopoietic toxicity (3.92 per 100 person-years vs 1.34 for TT or TC genotype; HR 2.92; 95% CI 1.57 to 5.41]), that remained significant after adjustment for race (2)
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