This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Aetiology

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Cystinosis is the most common cause in children. However, any form of renal tubular damage may be responsible, for example:

  • multiple myeloma

  • nephrotic syndrome

  • Sjogren's syndrome

  • other metabolic disorders such as:
    • Lowe's syndrome
    • galactosaemia
    • hereditary fructose intolerence
    • tyrosinaemia

  • following shock and major surgery

  • heavy metal poisoning:
    • lead
    • mercury
    • copper (Wilson's disease)

  • in nutritional disorders such as:
    • scurvy
    • kwashiorkor
    • nutritional rickets

  • drugs:
    • outdated tetracycline
    • cisplatin
    • salicylates

  • in medullary cystic disease

Note idiopathic Fanconi syndrome may occur:

  • autosomal dominant inheritance; presents in adults with osteomalacia, rickets and deteriorating renal function
  • treatment: calcitriol; phosphate, potassium, sodium bicarbonate supplements

Note that a Fanconi syndrome in association with hepatic dysfunction suggests Wilsons, tyrosinaemia or galactosaemia.


Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.