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Nephronophthisis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Nephronophthisis is a congenital disease of the kidney with unknown incidence, but known to be a significant cause of inherited chronic renal failure.

There is progressive cortical atrophy as a result of the development of cysts from the tubules.

Patients usually present in their first decade with:

  • polyuria
  • proteinuria
  • polydipsia
  • anaemia
  • growth failure

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