This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Defective lymphocytic function predisposes to increased susceptibility to infection which is usually detected by 3 to 6 months of age. Death within 2 years is common if untreated by marrow transplantation; transplant survivors are at increased risk of a variety of malignancies.

Both sexes are affected. Failure to thrive may be a non-specific presentation.

Common features include:

  • watery diarrhoea - associated with Salmonella and enteropathic E.coli
  • pulmonary infections - associated with Pseudomonas and Pneumocystis carnii
  • candidiasis - often around the mouth

Viral infections such as measles or chickenpox may be lethal.


Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.