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Epidemiology

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Wilms' is the most common malignancy of renal origin in children and accounts for approximately:

20% of all childhood malignancies
50% of all malignancies during infancy

Eighty percent occur before the age of 5 years, with a peak incidence at 2-3 years. The left kidney is affected more commonly than the right, with ten percent are bilateral. Boys are affected more commonly than girls. The incidence is approximately 1 in 10,000 live births which amounts to about 70 new cases per year in the UK.

All bilateral tumours and 15% of unilateral tumours are thought to be inherited.

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