it is marketed as co-danthrusate (when combined with docusate) and co-danthramer (when combined with poloxamer '188')
danthron is genotoxic and has been shown to be carcinogenic in rodent studies
the Committee on Safety on Medicines (CSM) has advised that the use of danthron-containing products be restricted to constipation in the terminally ill patients of all ages
Reference:
Current Problems in Pharmacovigilance (2000), 26, 4.
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