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Oxycodone
10mg oral oxycodone = 5mg SC oxycodone = 10mg SC morphine = 20mg oral morphine
Oxycodone has good oral bioavailability. The example above illustrates the dose conversion when oxycodone is regarded as being 2 times more potent than oral morphine.
Oxycodone is an alternative option if morphine is not tolerated.
Care should be taken to ensure clarity when prescribing immediate release capsules or modified release tablets. The modified release tablets also deliver a small dose which is immediate release.
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