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A randomised controlled trial with 12-month follow-up was undertaken at the infectious diseases department outpatient clinic in Oxford, UK. 60 consecutive patients with chronic fatigue syndrome were included in the study. Various exclusion criteria were used including if the patient was receiving psychotherapy or antidepressant drugs that reduced symptoms.
Half of the patients were allocated to medical care alone and half were allocated to cognitive behaviour therapy plus medical care. The latter group of patients exhibited improved function in comparison to the group receiving medical treatment alone (1)
NICE state that with respect to symptomatic management in ME (myalgic encephalitis)/chronic fatigue syndrome (CFS)
Cognitive behavioural therapy (CBT)
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